Research Article

Piperlongumine Induces Apoptosis and Synergizes with Cisplatin or Paclitaxel in Human Ovarian Cancer Cells

Figure 6

PL synergized with DDP in OVCAR3 ovarian cancer cells. (a) The growth histogram of OVCAR3 treated with the indicated PL and DDP. Cells were treated with PL (range from 0.1 to 1 μM) combined with DDP (0.1 to 1 μM) and cell survival was detected by MTT assay. The data were analyzed by CompuSyn software with the results showing dose-effect curve (b), CI values (c), and normalized isobologram (d).
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(a)
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(b)
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(c)
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(d)