Piperlongumine Induces Apoptosis and Synergizes with Cisplatin or Paclitaxel in Human Ovarian Cancer Cells
Figure 6
PL synergized with DDP in OVCAR3 ovarian cancer cells. (a) The growth histogram of OVCAR3 treated with the indicated PL and DDP. Cells were treated with PL (range from 0.1 to 1 μM) combined with DDP (0.1 to 1 μM) and cell survival was detected by MTT assay. The data were analyzed by CompuSyn software with the results showing dose-effect curve (b), CI values (c), and normalized isobologram (d).