Research Article

Olive (Olea europaea) Leaf Extract Induces Apoptosis and Monocyte/Macrophage Differentiation in Human Chronic Myelogenous Leukemia K562 Cells: Insight into the Underlying Mechanism

Figure 4

Induction of apoptosis in K562 cells treated with Chemlali Olive Leaf Extract (COLE). Cells were treated with 50, 100, and 150 μg/mL of COLE and incubated for different time. At the indicated time, K562 cells were stained with Annexin V and analyzed by flow cytometry. Control represents cells treated with 0.3% ethanol in medium. Results are represented as the mean ± SD of three independent experiments. *, **: significantly different from the control ( and , resp.).
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