Cardiovascular Complications of Sleep Apnea: Role of Oxidative Stress
Figure 2
OSA/IH can lead to oxidative stress, which through many mechanisms can cause endothelial function, which eventually progresses to atherosclerosis. eNOS: endothelial nitric oxide synthase, IH: intermittent hypoxia, LDL: low density lipoprotein, NO: nitric oxide, ONOO-: peroxynitrite, OSA: obstructive sleep apnea, OxLDL: oxidized low density lipoprotein, ROS: reactive oxygen species,.