Cyclovirobuxine D Attenuates Doxorubicin-Induced Cardiomyopathy by Suppression of Oxidative Damage and Mitochondrial Biogenesis Impairment

<div>CVB-D relieves DOX-induced apoptosis in cardiac cells. Representative photomicrographs of TUNEL stained heart section. (a) Arrows indicate TUNEL-positive cells, scale bar = 20 <i>μ</i>m. (b) Quantitative analysis of the percentage of apoptotic cells.</div>

Oxidative Medicine and Cellular Longevity

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Figure 3: Cyclovirobuxine D Attenuates Doxorubicin-Induced Cardiomyopathy by Suppression of Oxidative Damage and Mitochondrial Biogenesis Impairment 