Research Article

Daily Oxygen/O3 Treatment Reduces Muscular Fatigue and Improves Cardiac Performance in Rats Subjected to Prolonged High Intensity Physical Exercise

Table 1

Distance covered during 5 weeks of oxygen/ozone (O2/O3) treatment (2–6th week of the protocol) by rats subjected to a prolonged high intensity exercise.

Week 2Week 3Week 4Week 5Week 6Weeks 2–6
Mean s.e.m. (m/week)

ET + O2413 ± 23456 ± 32486 ± 12517 ± 32542 ± 10482.8 ± 21.8
ET + O2/O3 100462 ± 22503 ± 21521 ± 21563 ± 13587 ± 41 527.2 ± 23.6
ET + O2/O3 150513 ± 31549 ± 17559 ± 29611 ± 28639 ± 42 574.2 ± 29.4
ET + O2/O3 300559 ± 19601 ± 28641 ± 43708 ± 24735 ± 30 648.8 ± 28.8

The table shows the mean ± s.e.m. of the distance covered per single week and for the period of 5 weeks (2–6th week of the protocol) application of an oxygen/O3 mixture to the four experimental groups of trained rats. Ozone treatment at dose of 150 g/kg significantly increased () the distance covered compared to the control exercised ET + O2 rats. This effect was more evident at the dose of 300 g/kg, with a significance of versus ET + O2 at the same week. ET = exercise trained rats running on treadmill. Significant differences with respect to ET + O2 are shown as p < 0.05 and p < 0.01.