Research Article

Heterogeneity of Systemic Oxidative Stress Profiles in COPD: A Potential Role of Gender

Table 1

Anthropometric and clinical characteristics of 54 COPD patients.

COPD patients
()

Age (years)60 ± 7
Sex ratio (W/M)27/27
BMI (kg/m2)24.7 ± 4.1
Fat-free mass index (kg/m2)17.3 ± 2.3
Muscle mass index (kg/m2)7.9 ± 1.5
FEV1 (% pred.)54 ± 21
FEV1/FVC ratio53 ± 14
GOLD stages I/II/III/IV ()6/23/20/5
BODE score [18]2.1 ± 1.5
Breathlessness, MRC score1.5 ± 1.1
Tobacco consumption (packs/year)44 ± 24
Physical activity level, Voorips score [21]4.4 ± 3.2
6-MWD (m)518 ± 90
6-MWD (% pred.)81 ± 14
Wsl (% pred.)50 ± 19
VO2sl (% pred.)60 ± 16
QMVC (Nm)102 ± 37
QMVC (% pred.)75 ± 19
Qend (s)368 ± 152

Results are expressed in mean ± SD. COPD = chronic obstructive pulmonary disease; W = women/M = men; MRC = Medical Research Council; BODE index = body mass index, airway obstruction, dyspnoea, and exercise capacity index (6-MWD); BMI = body mass index (kg/m²); FEV1 (% pred.) = forced expiratory volume in 1 second; Wsl (% pred.) = symptom-limited power output; VO2sl (% pred.) = symptom-limited oxygen uptake; 6-MWD (m) = 6-minute walking distance; QMVC (Nm) = quadriceps maximal voluntary contraction expressed in Newtons; Qend (s) = quadriceps endurance time expressed in seconds.