Smooth Muscle Specific Overexpression of p22^phox Potentiates Carotid Artery Wall Thickening in Response to Injury

Figure 1

(a) Hematoxylin and eosin stained cross sections of carotid arteries harvested at selected time points following injury in C57BL/6J and mice. Representative sections from noninjured arteries ((A) and (B)) and carotid arteries 3 days after injury ((C) and (D)), 7 days after injury ((E) and (F)), and 14 days after injury ((G) and (H)) are shown. (b) Representative luminal images of fluo-4 treated sections of isolated carotid artery segments from a noninjured artery and injured arteries at days 0, 7, and 14 days following vascular injury. All images were obtained at a magnification of 200x and the scale bar is equal to 20 μm.

(a)

(b)