Smooth Muscle Specific Overexpression of p22^phox Potentiates Carotid Artery Wall Thickening in Response to Injury

Figure 4

(a) Effect of apocynin treatment on wall thickness 14 days after injury in and C57BL/6J mice. ^*Significant increase in mean wall thickness in C57BL/6J injured arteries versus C57BL/6J noninjured arteries (). ^†Significant increase in mean wall thickness in injured arteries versus noninjured arteries (). ^‡Significant decrease in mean wall thickness versus injured arteries from nontreated mice (). (b) Effect of apocynin treatment on the change in carotid artery cross-sectional wall area (CSWA) 14 days after injury in and C57BL/6J mice. ^*Significant increase in mean CSWA in injured arteries versus C57BL/6J injured arteries (). ^†Significant decrease in CSWA versus injured arteries from nontreated mice (). Values represent mean ± SEM for a minimum of 6 animals per group.

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