Research Article
Efficacy of N-Acetylcysteine, Glutathione, and Ascorbic Acid in Acute Toxicity of Paraoxon to Wistar Rats: Survival Study
Table 1
Mortality [%] after concurrent application of paraoxon, pralidoxime, and NEAO.
| Groups (G) | POX dose μmol/rat | 30 min | 1 hour | 2 hours | 3 hours | 4 hours | 24 hours | 48 hours |
| G1: POX only | 1/2 | 79/96 | 83/96 | 88/96 | 88/96 | 88/96 | 88/96 | 88/96 | G2: POX + PAM + NAC | 1/2 | 42/78 | 50/78 | 67/89 | 71/89 | 71/89 | 79/89 | 83/94 | G3: POX + NAC | 1/2 | 92/100 | 92/100 | 100/100 | 100/100 | 100/100 | 100/100 | 100/100 | G4: POX + PAM | 1/2 | 8/75 | 8/79 | 13/79 | 17/79 | 25/79 | 25/83 | 29/83 | G5: POX + PAM + GSH | 1/2 | 75/75 | 83/75 | 92/83 | 92/92 | 92/96 | 92/96 | 96/96 | G6: POX + GSH | 1/2 | 100/100 | 100/100 | 100/100 | 100/100 | 100/100 | 100/100 | 100/100 | G7: POX + PAM + AA | 1/2 | 67/83 | 67/88 | 79/88 | 83/92 | 88/92 | 92/92 | 92/92 | G8: POX + AA | 1/2 | 75/100 | 88/100 | 88/100 | 88/100 | 88/100 | 88/100 | 88/100 |
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