Polyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related Diseases

Figure 1

As an individual ages, the balance between a long, healthy lifespan and suffering age-related diseases is believed to be related to the interplay between the cellular antioxidant defence system and adverse effects related to oxidative stress. In aging cells, oxidative stress increases due to a progressive decline in the efficiency of antioxidant defence systems. There is convincing evidence to indicate that supplementation with polyphenols, such as stilbenes, anthocyanins, and catechins, can increase cellular antioxidant defence and promote health of the individual.