Preventive Treatment with Ketamine Attenuates the Ischaemia-Reperfusion Response in a Chronic Postischaemia Pain Model

Figure 4

Cold allodynia of KE, MP, and NS groups on the ipsilateral (a) and contralateral side (b) from baseline before ischaemia until 7 days after reperfusion. On the ipsilateral side, the withdrawal threshold to acetone of group KE was significantly higher, compared with groups NS () and MP (). On the contralateral side, the withdrawal threshold to acetone was significantly higher in KE () and MP () groups than that of NS; ; .

(a)

(b)