Research Article
Cytokine Dysregulation in MECP2- and CDKL5-Related Rett Syndrome: Relationships with Aberrant Redox Homeostasis, Inflammation, and ω-3 PUFAs
Figure 7
Systemic redox status in MECP2- and CDKL5-mutated Rett patients before and after ω-3 PUFAs supplementation. Data are expressed as means ± standard deviations. Asterisks denote significant post hoc pairwise tests (). P-NPBI: plasma non-protein-bound iron; F2-IsoPs: plasma F2-isoprostanes; F2-dihomo-IsoPs: plasma F2-dihomo-isoprostanes; F4-NeuroPs: plasma F4-neuroprostanes; GSH: reduced glutathione; GSSG: oxidized glutathione. The dashed line denotes upper range limit from laboratory normal reference values.
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