Intracellular Oxidant Activity, Antioxidant Enzyme Defense System, and Cell Senescence in Fibroblasts with Trisomy 21

Figure 5

Antioxidant enzyme activities in fibroblasts with trisomy 21 (T21F) () and controls (CF) (). Enzymatic activities in cell lysates were determined as described in Methods section. Results at low (a) and high (b) passages are expressed as mean ± SEM of 12 separate experiments performed in triplicate. Statistical differences between T21F and CF were analyzed by Student’s -test; ; ; .

(a)

(b)