Antihyperglycemic Potential of Grewia asiatica Fruit Extract against Streptozotocin-Induced Hyperglycemia in Rats: Anti-Inflammatory and Antioxidant Mechanisms

Table 4

Effect of G. asiatica fruits extract on lipid peroxidation (MDA), reduced glutathione (GSH), and superoxide dismutase (SOD) enzyme activities in hyperglycemic rats.

Experimental groups	Control	Hyperglycemic	Hyperglycemic + G. asiatica (100 mg/kg)	Hyperglycemic + G. asiatica (200 mg/kg)
MDA (mol/g tissue)	71.62 ± 5.95	113.89 ± 8.73	81.14 ± 6.61	75.50 ± 6.31
GSH (mg/g tissue)	56.18 ± 5.59	33.88 ± 3.37	49.76 ± 4.77	53.33 ± 4.97
SOD (U/g tissue)	66.25 ± 4.89	37.50 ± 3.47	59.89 ± 5.20	63.94 ± 4.77

Results represent mean of 8 rats ± SED.
^aSignificant difference between control and hyperglycemic groups.
^bSignificant difference between hyperglycemic and hyperglycemic treated groups.
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