Effect of Melatonin Intake on Oxidative Stress Biomarkers in Male Reproductive Organs of Rats under Experimental Diabetes

Figure 1

Experimental design of the study. Melatonin was offered in the drinking water (10 μg/kg b.w), and diabetes was induced by streptozotocin injection (4.5 mg/100 g b.w., i.p.). C1: one-week control; M1: one-week control treated with melatonin; D1: one-week diabetic; MD1: one-week diabetic treated with melatonin; C2: two-month control; M2: two-month control treated with melatonin; D2: two-month diabetic; MD2: two-month diabetic treated with melatonin ( animals/group). The euthanasia was performed at 13 weeks of age for short-term experiment and at 21 weeks of age for long-term experiment.