Research Article

Urinary F2-Isoprostanes and Metabolic Markers of Fat Oxidation

Table 1

Characteristics of the study population ( = 682).

CharacteristicsMean (SD) or number (%)

Age (years)54.5 (8.4)
Sex, female (number, %)385 (56.5)
Ethnicity (number, %)
 Non-Hispanic White291 (43)
 African American174 (25)
 Hispanic White217 (32)
Normal glucose tolerance, NGT (number, %)226 (33)
Impaired glucose tolerance IGT (number, %)456 (67)
BMI (kg/m2)
 Normal (<25)179 (26)
 Overweight (25–29.9)303 (44)
 Obese (≥30)199 (29)
 Missing1
iPF2α-III (ng/mg creatinine) 0.25 (0.20)
2,3-dinor-iPF2-III (ng/mg creatinine) 4.32 (3.05)
iPF2-VI (ng/mg creatinine) 6.46 (4.08)
8,12-iso-iPF2α-VI (ng/mg creatinine) 4.19 (2.92)
F2-isoprostane composite index1.41 (0.80)
Acetylcarnitine, C2 (nmole/g)7.16 (2.45)
Propionylcarnitine, C3 (nmole/g)0.37 (0.12)
Butyrylcarnitine, C4 (nmole/g)0.19 (0.11)
Valerylcarnitine, C5 (nmole/g)0.15 (0.05)
Octanoylcarnitine, C8 (nmole/g)0.17 (0.12)
Decanoylcarnitine, C10 (nmole/g)0.33 (0.29)
Dodecanoylcarnitine, C12 (nmole/g)0.21 (0.11)

Mean (SD) presented for continuous variables; F2-isoprostane composite index was calculated using all four F2-isoprostane measurements as follows: each value was standardized (divided by the standard deviation) and mean of the four standardized values was calculated for each participant.