Urinary F2-Isoprostanes and Metabolic Markers of Fat Oxidation

Table 2

Association between F2-isoprostane index and selected acylcarnitines ( = 682).

Acylcarnitines	Beta coefficient (95% CI)
	Minimally adjusted model	Fully adjusted model
Acetylcarnitine, C2	0.098 (0.042, 0.154)	0.109 (0.051, 0.167)
Propionylcarnitine, C3	−0.027 (−0.089, 0.034)	−0.024 (−0.088, 0.040)
Butyrylcarnitine, C4	−0.010 (−0.067, 0.048)	−0.010 (−0.069, 0.049)
Valerylcarnitine, C5	−0.093 (−0.156, −0.030)	−0.094 (−0.159, −0.029)
Octanoylcarnitine, C8	0.010 (−0.046, 0.066)	0.014 (−0.044, 0.073)
Decanoylcarnitine, C10	0.016 (−0.040, 0.071)	0.020 (−0.039, 0.079)
Dodecanoylcarnitine, C12	0.065 (0.009, 0.122)	0.072 (0.013, 0.132)

Beta coefficients show differences in F2-isoprostanes index associated with a change in acylcarnitines (log-transformed) equal to standard deviation. Minimally adjusted models included the demographic variables (age, gender, and race/ethnicity) and BMI; fully adjusted models included additional metabolic variables (IGT-status, insulin sensitivity, and AIR). Statistically significant results ( < 0.05) are in bold.