Genome-Wide Expression Profiling of Anoxia/Reoxygenation in Rat Cardiomyocytes Uncovers the Role of Mito<svg xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-4.1996pt" id="M1" height="15.332pt" version="1.1" viewBox="-0.0657574 -11.1324 35.4805 15.332" width="35.4805pt"><g transform="matrix(.017,0,0,-0.017,0,0)"><path id="g187-76" d="M699 0V35C659 41 632 57 591 109C519 200 445 301 381 397C426 443 468 491 527 545C582 597 623 609 685 615V650H425V615L443 613C490 607 492 592 468 561C435 516 395 467 328 399C298 368 273 352 252 346V516C252 602 260 608 331 615V650H37V615C112 608 121 602 121 516V134C121 48 111 42 39 35V0H338V35C261 42 252 48 252 134V314C267 316 280 310 301 280C372 176 455 59 498 0H699Z"/></g><g transform="matrix(.012,0,0,-0.012,12.108,4.134)"><path id="g187-66" d="M687 0V35C623 43 611 56 577 144C512 316 450 490 386 665L335 652L130 138C97 54 84 43 18 35V0H242V35C169 44 166 58 181 106C193 146 206 182 217 213H409C424 173 439 130 449 100C465 56 460 44 401 35V0H687ZM390 266H234C260 337 285 410 313 483H316L390 266Z"/></g><g transform="matrix(.012,0,0,-0.012,19.709,4.134)"><path id="g187-85" d="M616 481C611 545 606 633 605 675H580C563 656 549 650 523 650H121C92 650 79 653 64 675H39C37 624 31 551 27 478H64C77 528 89 562 106 579C120 596 138 606 221 606H255V133C255 48 245 42 161 35V0H487V35C399 42 389 48 389 133V606H434C493 606 518 601 536 583S568 531 580 479L616 481Z"/></g><g transform="matrix(.012,0,0,-0.012,27.408,4.134)"><path id="g187-81" d="M42 650V615C112 608 121 601 121 516V133C121 48 112 41 37 34V0H347V34C262 41 253 48 253 133V271L321 254C332 254 347 254 362 256C468 269 567 330 567 464C567 529 540 579 493 611C453 639 397 650 318 650H42ZM253 570C253 585 255 595 262 601C268 606 280 611 299 611C360 611 423 574 423 461C423 326 343 300 307 300C286 300 265 305 253 310V570Z"/></g></svg> in Energy Homeostasis

<div>ATP quantitation. At the end of reoxygenation, ATP content was detected by HPLC at a detection wavelength of 254 nm. Protein content was also measured by using the same sample. ATP level of each sample was normalized to protein content of the same sample. Data are mean ± SD. <svg height="8.55521pt" id="M93" style="vertical-align:-0.2063904pt" version="1.1" viewbox="-0.0498162 -8.34882 27.8368 8.55521" width="27.8368pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M495 86L479 114C446 82 419 66 409 66C401 66 401 72 406 97C420 166 436 231 453 297C489 435 454 448 428 448C406 448 384 439 354 422C305 394 222 327 161 247H159L183 345C200 415 194 448 173 448C143 448 82 410 23 351L38 325C64 349 95 371 105 371C111 371 116 365 109 336L25 -4L31 -12C50 -4 77 3 107 9C119 69 132 122 145 168C197 254 321 381 370 381C387 381 393 374 378 305L329 95C309 17 320 -12 345 -12C372 -12 430 19 495 86Z" id="g113-111"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="502" vert-adv-y="502"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,10.158,0)"><path d="M535 323V373H52V323H535ZM535 138V188H52V138H535Z" id="g117-34"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="587" vert-adv-y="587"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,21.421,0)"><path d="M285 378C315 398 338 416 353 432C373 451 384 474 384 503C384 579 325 635 236 635H235C182 635 136 610 108 579L65 516L85 496C110 533 150 575 205 575C258 575 300 543 300 481C300 407 232 369 141 339L147 310C163 315 188 321 211 321C268 321 338 284 338 192C338 94 288 40 217 40C160 40 119 68 93 91C85 98 77 97 69 91C60 84 47 71 46 58C44 46 48 35 62 22C75 10 116 -12 162 -12C234 -12 424 62 424 224C424 297 373 359 285 376V378Z" id="g113-52"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="480" vert-adv-y="480"></glyph.data></g></svg> for each group. <svg height="15.7176pt" id="M94" style="vertical-align:-3.833899pt" version="1.1" viewbox="-0.0498162 -11.8837 49.0276 15.7176" width="49.0276pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M364 493V518L231 520L258 659L234 665L176 533L55 613L40 592L144 490L42 396L56 374L178 451L248 321L271 330L232 468L364 493Z" id="g190-43"></path><glyph.data ascent="989" descent="-360" horiz-adv-x="404" vert-adv-y="404"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,4.188,0)"><path d="M600 480C600 590 528 650 384 650H143L137 622C222 614 225 607 210 531L130 127C113 41 106 36 23 28L17 0H294L300 28C204 36 195 42 212 127L243 284L314 263C327 263 339 263 352 264C465 271 600 337 600 480ZM508 481C508 351 402 304 329 304C289 304 265 311 250 317L295 559C302 594 310 606 323 611C335 616 350 619 367 619C455 619 508 573 508 481Z" id="g113-81"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="617" vert-adv-y="617"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,15.846,0)"><path d="M512 -3V55L134 254V256L512 456V514L75 281V230L512 -3Z" id="g117-91"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="587" vert-adv-y="587"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,27.109,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z" id="g113-49"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="480" vert-adv-y="480"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,33.349,0)"><path d="M113 -12C146 -12 170 11 170 46C170 78 146 103 114 103S58 78 58 46C58 11 82 -12 113 -12Z" id="g113-47"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="228" vert-adv-y="228"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,36.313,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z" id="g113-49"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="480" vert-adv-y="480"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,42.553,0)"><path d="M153 550H386L412 615L406 623H120L82 318C104 327 142 338 184 338C294 338 347 275 347 187C347 112 305 39 221 39C160 39 119 71 97 89C88 97 80 96 71 90C59 80 50 67 49 57C48 45 52 36 66 23C80 9 123 -12 169 -12C221 -11 288 15 342 59C403 109 431 165 431 225C431 308 366 395 238 395C212 395 165 379 127 364L153 550Z" id="g113-54"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="480" vert-adv-y="480"></glyph.data></g></svg>.</div>

Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Genome-Wide Expression Profiling of Anoxia/Reoxygenation in Rat Cardiomyocytes Uncovers the Role of Mito<svg xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-4.1996pt" id="M1" height="15.332pt" version="1.1" viewBox="-0.0657574 -11.1324 35.4805 15.332" width="35.4805pt"><g transform="matrix(.017,0,0,-0.017,0,0)"><path id="g187-76" d="M699 0V35C659 41 632 57 591 109C519 200 445 301 381 397C426 443 468 491 527 545C582 597 623 609 685 615V650H425V615L443 613C490 607 492 592 468 561C435 516 395 467 328 399C298 368 273 352 252 346V516C252 602 260 608 331 615V650H37V615C112 608 121 602 121 516V134C121 48 111 42 39 35V0H338V35C261 42 252 48 252 134V314C267 316 280 310 301 280C372 176 455 59 498 0H699Z"/></g><g transform="matrix(.012,0,0,-0.012,12.108,4.134)"><path id="g187-66" d="M687 0V35C623 43 611 56 577 144C512 316 450 490 386 665L335 652L130 138C97 54 84 43 18 35V0H242V35C169 44 166 58 181 106C193 146 206 182 217 213H409C424 173 439 130 449 100C465 56 460 44 401 35V0H687ZM390 266H234C260 337 285 410 313 483H316L390 266Z"/></g><g transform="matrix(.012,0,0,-0.012,19.709,4.134)"><path id="g187-85" d="M616 481C611 545 606 633 605 675H580C563 656 549 650 523 650H121C92 650 79 653 64 675H39C37 624 31 551 27 478H64C77 528 89 562 106 579C120 596 138 606 221 606H255V133C255 48 245 42 161 35V0H487V35C399 42 389 48 389 133V606H434C493 606 518 601 536 583S568 531 580 479L616 481Z"/></g><g transform="matrix(.012,0,0,-0.012,27.408,4.134)"><path id="g187-81" d="M42 650V615C112 608 121 601 121 516V133C121 48 112 41 37 34V0H347V34C262 41 253 48 253 133V271L321 254C332 254 347 254 362 256C468 269 567 330 567 464C567 529 540 579 493 611C453 639 397 650 318 650H42ZM253 570C253 585 255 595 262 601C268 606 280 611 299 611C360 611 423 574 423 461C423 326 343 300 307 300C286 300 265 305 253 310V570Z"/></g></svg> in Energy Homeostasis 

Oxidative Medicine and Cellular Longevity

Genome-Wide Expression Profiling of Anoxia/Reoxygenation in Rat Cardiomyocytes Uncovers the Role of Mito in Energy Homeostasis

Figure 5