Genome-Wide Expression Profiling of Anoxia/Reoxygenation in Rat Cardiomyocytes Uncovers the Role of Mito in Energy Homeostasis

Table 5

DEGs highly enriched and energy related pathways.

Pathway name^a	Pathway ID	Con versus A/R			A/R versus DZ			DZ versus DZ5HD
		DEGs with pathway annotation (335)	value^b	value^c	DEGs with pathway annotation (467)	value^b	value^c	DEGs with pathway annotation (361)	value^b	value^c
Proteasome	ko03050	14 (4.18%)			20 (4.28%)			16 (4.43%)
Fatty acid metabolism	ko00071	8 (2.39%)			14 (3%)			9 (2.49%)
Peroxisome	ko04146	13 (3.88%)			17 (3.64%)			12 (3.32%)
PPAR signaling pathway	ko03320	14 (4.18%)			16 (3.43%)			14 (3.88%)
TCA cycle	ko00020	7 (2.09%)			14 (3%)			12 (3.32%)

Pathway analysis based on KOBAS server 2.0 [21, 22].
value in hypergeometric test; is considered as DGEs highly enriched.
^cThe value is similar to the well-known - value, except it is a measure of significance in terms of the false discovery rate rather than the false positive rate [23].