Cardiac H₂S Generation Is Reduced in Ageing Diabetic Mice

Figure 1

Fifteen months of high-fructose feeding increases fasting blood glucose levels and reduces insulin sensitivity and glucose tolerance in mice. (a) Fasting blood glucose levels of control and high-fructose-fed mice at the beginning and after 15 months of the experimental period. (b) Representative glucose tolerance test curves for control and high-fructose-fed mice after 15 months. (c) Area under the curve (AUC) of glucose tolerance test results was determined for each animal using the trapezoidal rule. (d) Representative insulin tolerance test curves for control and high-fructose-fed mice after 15 months. (e) Area under the curve (AUC) of insulin tolerance test results was determined for each animal using the trapezoidal rule. Results are means ± SEM. versus control; versus control.

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