Differential Regulation of the Extracellular Cysteine/Cystine Redox State (E_hCySS) by Lung Fibroblasts from Young and Old Mice

Figure 4

Time course of restoration by young and old fibroblasts after challenge with oxidizing or reducing media. Lung fibroblasts from young and old mice were incubated with either 0 mV media or −150 mV media for 0, 1, or 4 hours. Conditioned media were removed and analyzed for Cys and CySS concentrations by HPLC.