Research Article

The Impact of Lipoprotein-Associated Oxidative Stress on Cell-Specific Microvesicle Release in Patients with Familial Hypercholesterolemia

Table 2

Plasma levels of circulating MVs.

Controls ()FH () value

Total MVs15603 (10549–45211)35616 (23409–58075)0.022
Total CD36+ MVs2161 (1274–3213)2754 (1704–3772)NS
EMVs157 (119–238)282 (204–522)0.002
CD36+ EMVs143 (85–212)212 (170–408)0.008
PMVs2020 (1387–2876)1664 (1382–2773)NS
CD36+ PMVs1758 (1229–2475)1482 (1219–2482)NS
MMVs5 (3–11)10 (7–14)0.004
CD36+ MMVs3 (2–4)5 (4–8)0.001
ErytMVs207 (147–282)296 (193–453)0.043
CD36+ ErytMVs8 (3–13)11 (6–15)NS
TF+ MPs225 (204–396)408 (327–451)0.006

Values (MVs μL−1 plasma) are shown as the median (interquartile range). MVs, microvesicles; MMVs, monocyte-derived MVs; EMVs, endothelial cell-derived MVs; PMVs, platelet-derived MVs; ErytMVs, erythrocyte-derived MVs; CD36, scavenger receptor CD36; TF, tissue factor.