Research Article

The Impact of Lipoprotein-Associated Oxidative Stress on Cell-Specific Microvesicle Release in Patients with Familial Hypercholesterolemia

Table 3

Multiple regression analysis with oxLDL-C and gender as independent variables.

ControlsFH ATX−FH ATX+
value value value

= 0.05 = 0.03 = 0.76

Total CD36+ MVs
 oxLDL-C−0.07NS0.16NS0.94<0.001
 Gender0.18NS−0.08NS0.530.004

= 0.01 = 0.03 = 0.64

CD36+ PMVs
 oxLDL-C−0.08NS0.11NS0.88<0.001
 Gender0.04NS−0.13NS0.32NS

= 0.09 = 0.16 = 0.41

CD36+ MMVs
 oxLDL-C0.06NS0.30NS0.580.027
 Gender0.33NS0.24NS0.600.024

= 0.08 = 0.01 = 0.68

CD36+ EMVs
 oxLDL-C−0.20NS0.02NS0.90<0.001
 Gender0.14NS−0.07NS0.390.041

= 0.04 = 0.16 = 0.51

CD36+ ErytMVs
 oxLDL-C−0.19NS0.26NS0.780.003
 Gender0.03NS0.28NS0.27NS

The standardized regression coefficients beta () is included as a measure of how strongly each predictor variable influences the criterion (dependent) variable. values are two-sided and considered significant when <0.05. See Table 2 for abbreviations.