Spironolactone Effect in Hepatic Ischemia/Reperfusion Injury in Wistar Rats

Figure 1

Dose-response study of spironolactone on hepatic injury in total normothermic IR. The effects of SPI treatment on ALT and AST levels were assessed. Rats were treated with SPI (0, 1,000, 2,600, 5,000, 10,000, and 20,000 μg/kg). Transaminase levels were measured after 1 h of reperfusion. Means without a common letter are different; .