Bioavailability Study of an Innovative Orobuccal Formulation of Glutathione

Table 2

GSH absorption.

	GSH (mg)		GSH (%)
Applied amount	0.125
	Mean value	SD	Partial absorption	Total absorption	SD
T10 (medium)	0.069	0.002	55.04%	55.04%	1.9%
T20 (medium)	0.015	0.0008	12.32%	67.36%	0.63%
T30 (medium)	0.003	0.0002	2.56%	69.92%	0.14%
Tissue	0.001	0.0001	1%	1%	0.17%
Total absorption	0.088	0.0031	70.92%	70.92%	0.17%

In vitro data obtained from GSH dosage in the experimental model are reported. The applied and measured GSH amounts are expressed as mg (mean ± standard deviation SD) in the collected medium at different times and homogenized tissue at the end of experimental period. The (%) absorption values, calculated on GSH applied amount, both partial absorption related to each single monitored experimental time and total absorption (the sum of the % in the consecutive times), are calculated and reported in the table too.