Research Article

Bioavailability Study of an Innovative Orobuccal Formulation of Glutathione

Table 4

GSH level.

Absorption times
BasalT30T60
(nmol/g Hb)(nmol/g Hb)(nmol/g Hb)

Mean735885028913
SD159013031309

value0.014 ()

In vivo data obtained from the GSH dosage in total blood are reported. Results are expressed as mean ± SD and expressed in nmol GSH per gram of Hb at different experimental times T30 and T60 versus basal (before starting orobuccal fast-slow release tablet absorption). Statistical analysis was carried out using repeated measures analysis of variance in order to compare the mean values at subsequent times. The GSH level increased significantly () with absorption time.