Maladaptive Modulations of NLRP3 Inflammasome and Cardioprotective Pathways Are Involved in Diet-Induced Exacerbation of Myocardial Ischemia/Reperfusion Injury in Mice

Table 1

General parameters of mice after 12 weeks of Control or high-fat high-fructose (HFHF) diets.

	Control; ()	HFHF; ()
Body weight increase; (g)	8.5 ± 1.6	14.7 ± 3.2
Heart weight; (% of body w.)	0.45 ± 0.02	0.35 ± 0.06
Plasma glucose; (mg/dL)	73 ± 19	139 ± 13
Plasma insulin; (mg/mL)	85.8 ± 5.3	106.8 ± 6.8
Plasma TG; (mg/dL)	32.8 ± 7.8	66.5 ± 25.5
Plasma Chol.; (mg/dL)	77.2 ± 5.7	97.2 ± 8.2

Data are means ± SD. , versus Control.