Targeting Pin1 Protects Mouse Cardiomyocytes from High-Dose Alcohol-Induced Apoptosis

Figure 3

Overexpression of Pin1 enhanced alcohol-induced cardiomyocyte apoptosis. (a) Pin1 protein expression measured by western blotting after Pin1 plasmid transfection. Cell ability (b), caspase-9 and caspase-3 activity assay (c), and TUNEL staining (d) in Pin1-overexpressed cardiomyocytes treated or untreated with alcohol (50 mM) for 24 h. , , and .

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