PON-1 Activity and Plasma 8-Isoprostane Concentration in Patients with Angiographically Proven Coronary Artery Disease
Table 3
8-Iso-PGF2α concentration according to serum arylesterase and paraoxonase activity quartiles.
Paraoxonase (PONase) [U/L]
Arylesterase (AREase) [kU/L]
Quartile 1
Quartile 2
Quartile 3
Quartile 4
Quartile 1
Quartile 2
Quartile 3
Quartile 4
All subjects
Range
<98
98–135
135–224
≥225
<87
87–107
107–122
≥123
8-Iso-PGF2α [pg/mL]
134 (130–196)
114 (89–157)
103 (74–146)
104 (69–154)
140 (100–200)
103 (70–162)
117 (74–148)
118 (83–168)
CAD+
Range
<98
98–123
123–192
≥193
<83
83–103
103–123
≥123
8-Iso-PGF2α [pg/mL]
145 (88–158)
113 (78–161)
112 (88–158)
123 (84–169)
142 (103–205)
122 (89–184)
121 (75–157)
114 (76–168)
CAD−
Range
<112
112–201
201–271
≥272
<98
98–108
108–130
≥130
8-Iso-PGF2α [pg/mL]
124 (70–170)
92 (49–125)
92 (74–130)
110 (71–137)
133 (80–153)
95 (69–133)
103 (74–119)
92 (72–149)
8-Iso-PGF2α concentrations are presented as median (25th and 75th percentiles); compared with Quartile 1; CAD+ patients with coronary artery disease and CAD− patients with negative result of coronary angiography.