Research Article
PON-1 Activity and Plasma 8-Isoprostane Concentration in Patients with Angiographically Proven Coronary Artery Disease
Table 4
Concentration of 8-iso-PGF2α and PONase and AREase activity in patients with and without traditional risk factors.
| | 8-Iso-PGF2α [pg/mL] | value | Paraoxonase (PONase) [U/L] | value | Arylesterase (AREase) [kU/L] | value |
| Hypertension/nonhypertension | | | | | | | All subjects | 122 (80–170)/101 (79–137) | 0.124 | 125 (93–202)/186 (104–234) | 0.065 | 105 ± 26/112 ± 24 | 0.159 | CAD+ | 134 (94–195)/101 (78–141) | 0.045 | 121 (89–177)/152 (100–233) | 0.501 | 102 ± 20/110 ± 26 | 0.218 | CAD− | 95 (69–138)/112 (80–133) | 0.295 | 183 (99–272)/210 (201–311) | 0.484 | 113 ± 23/114 ± 23 | 0.841 | Diabetes/nondiabetes | | | | | | | All subjects | 120 (74–162)/116 (80–163) | 0.894 | 104 (65–163)/153 (102–240) | <0.001 | 105 ± 25/108 ± 26 | 0.827 | CAD+ | 126 (100–164)/120 (89–178) | 0.694 | 104 (69–176)/125 (99–202) | 0.049 | 102 ± 26/104 ± 23 | 0.761 | CAD− | 110 (71–119)/95 (72–135) | 0.293 | 116 (64–140)/227 (127–306) | 0.004 | 115 ± 25/115 ± 23 | 0.704 | Smoking/nonsmoking | | | | | | | All subjects | 126 (89–178)/113 (70–137) | 0.006 | 123 (93–201)/182 (109–264) | 0.012 | 102 ± 26/112 ± 24 | 0.044 | CAD+ | 140 (89–198)/116 (73–141) | 0.042 | 131 (90–225)/119 (88–191) | 0.074 | 99 ± 26/108 ± 24 | 0.153 | CAD− | 117 (90–138)/89 (66–133) | 0.223 | 163 (96–238)/228 (140–300) | 0.073 | 114 ± 20/117 ± 24 | 0.680 |
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Values are presented as mean ± SD or as median (25th and 75th percentiles). Student’s -test; Mann-Whitney test.
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