Creatine Prevents the Structural and Functional Damage to Mitochondria in Myogenic, Oxidatively Stressed C2C12 Cells and Restores Their Differentiation Capacity

Figure 3

Protective effect of Cr on cardiolipin peroxidation induced by oxidative challenge in differentiating C2C12 myoblasts. Flow cytometric analysis of the cardiolipin-sensitive probe 10-nonyl acridine orange (NAO) was used to monitor changes in mitochondrial lipid peroxidation in differentiating oxidatively challenged C2C12 cells pretreated with 0 or 3 mM Cr. Analysis was performed at DifD2. Data are the means SD. ; compared to control ().