Curcumin Supplementation Decreases Intestinal Adiposity Accumulation, Serum Cholesterol Alterations, and Oxidative Stress in Ovariectomized Rats

Table 2

Serum parameters and lipid profile.

	Sham	OVX	Curcumin (mg/Kg/day)
			OVX 50	OVX 100
IL-6 (pg/mL)	74.73 ± 1.08	78.80 ± 0.65	75.96 ± 0.56	75.39 ± 0.72
AST activity (U/dL)	18.937 ± 1.72	26.888 ± 1.37	25.507 ± 1.22	26.975 ± 0.98
ALT activity (U/dL)	16.974 ± 0.67	16.753 ± 0.68	16.739 ± 0.48	16.979 ± 0.91
HDL (mg/dL)	30.714 ± 1.99	31.666 ± 1.55	31.285 ± 1.12	29.857 ± 1.47
LDL (mg/dL)	17.285 ± 2.74	26.933 ± 3.40	26.171 ± 1.36	23.742 ± 1.46
VLDL (mg/dL)	9.428 ± 1.19	8.222 ± 0.75	5.714 ± 0.42	6.285 ± 0.86
Total cholesterol (mg/dL)	54.750 ± 3.56	70.888 ± 4.41	63.857 ± 2.67	59.714 ± 3.04
Total triglycerides (mg/dL)	47.142 ± 5.88	40.888 ± 2.27	27.714 ± 2.07	30.571 ± 4.41

IL-6 levels, AST/ALT activities, and lipid profile were measured in serum samples. Sham and OVX groups were treated once a day for 30 days with refined olive oil containing or not curcumin. Data are expressed as mean ± SEM (sham , OVX , OVX50 , OVX100 ).
Statistically different from Sham group: < 0.05, < 0.01 < 0.001; < 0.05: different from OVX group (one-way ANOVA followed by Tukey’s test).
ALT: alanine aminotransferase; AST: aspartate aminotransferase; HDL: high-density lipoprotein; IL-6: interleukin-6; LDL: low-density lipoprotein; OVX: ovariectomized; VLDL: very low-density lipoprotein.