Mitochondrial Alterations in Peripheral Mononuclear Blood Cells from Alzheimer’s Disease and Mild Cognitive Impairment Patients

Figure 6

Correlation between CYT C, PGC-1α, or TFAM proteins with cognitive decline. The values of CYT C (a), PGC-1α (b), or TFAM (c) in protein extracts derived from PBMCs were correlated with the corresponding values of MMSE score. ng of CYT C/MMSE, , ; ng of PGC-1α/MMSE, , ; ng of TFAM/MMSE, , . (d) The values of TFAM were also correlated with the corresponding values of mtDNA content (, ).

(a)

(b)

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