Mitochondrial Alterations in Peripheral Mononuclear Blood Cells from Alzheimer’s Disease and Mild Cognitive Impairment Patients
Table 1
Demographic and clinical characteristics of subjects/patients used in the study.
(a) Spanish cohort
CTL
MCI
AD
(M; F)
30 (16; 14)
24 (14; 10)
20 (8; 12)
Mean age ± SD (years)
71 ± 8
73 ± 6
74 ± 7
MMSE
29 ± 1
27 ± 2
24 ± 3
CDR
0
0.5
1
Disease onset
71.7 ± 6.49
71.67 ± 8.27
LOI (months)
24.5 ± 14.36
26.8 ± 13.25
(b) Italian cohort
CTL
MCI
AD
(M; F)
248 (116; 131)
70 (44; 26)
276 (99; 177)
Mean age ± SD (years)
75 ± 9.98
71 ± 8.71
78.23 ± 7.37
MMSE
29 ± 1
25.3 ± 4.45
15.1 ± 6.23
CDR
0
0.52 ± 0.06
2 ± 1
Disease onset
69.6 ± 6.2
72.5 ± 7.5
LOI (months)
30.2 ± 12.3
43 ± 31
AD: Alzheimer’s disease; CTL: control; F: female; M: male; MMSE: Mini-Mental State Examination; CDR: Clinical Dementia Rating; LOI: length of illness; and : number. Data are expressed as mean ± SD.