Research Article
Critical Role of FoxO1 in Granulosa Cell Apoptosis Caused by Oxidative Stress and Protective Effects of Grape Seed Procyanidin B2
Table 1
Scheme of the experiment to study the protective role of GSPB2 in diquat-induced oxidative damage.
| Group | Treated with | Treatment time |
| Control (I) | Saline (orally, once daily) | 21 days |
| Control + GSPB2 (II) | GSPB2 (30 mg/kg, orally, once daily) | 21 days |
| Diquat (III) | Saline (as in group I) + diquat (8 mg/kg, i.p. twice weekly) | Saline treatment for 7 days and then treatment with diquat for two weeks |
| Diquat + GSPB2 (IV) | GSPB2 (as in group II) + diquat (as in group III) |
GSPB2 treatment for 21 days, on day 7, treated with diquat for two weeks |
|
|