Research Article

Cytoprotective and Cytotoxic Effects of Rice Bran Extracts in Rat H9c2(2-1) Cardiomyocytes

Table 4

Average IC50 of H2O2 for H9c2(2-1) cells. The IC50 value was determined from respective cell viability curves (Figure 6) via GraphPad Prism (GraphPad Software, Inc., USA). Data represent mean standard deviation of 3 technical replicates (). “” denotes significant difference from negative control treated with media + 1% EtOH at . Graphical representations of data were depicted in Figure 5.

Average IC50 of H2O2 (µM)
Log [H2O2]H2O2

Control sample
 Negative control
 (media + 1% EtOH)
2.50 ± 0.01316.23 1.02
RBE
 BJLN (25 µg/mL)2.81 ± 0.04645.65 1.10
 BJLN (50 µg/mL)1.97 ± 0.0792.90 1.17
 MR219 (50 µg/mL)2.55 ± 0.06320.63 1.14
 MR219 (100 µg/mL)2.24 ± 0.05171.79 1.13