Association of Nuclear Factor-Erythroid 2-Related Factor 2, Thioredoxin Interacting Protein, and Heme Oxygenase-1 Gene Polymorphisms with Diabetes and Obesity in Mexican Patients
Table 4
Genotype frequency of the rs7211 polymorphism in subjects without diabetes and women.
Obese
Nonobese
Crude OR (95% CI)
Adjusted OR (95% CI)
Nondiabetic
CC
189 (56.6)
339 (53.4)
Reference
Reference
CT
133 (40)
241 (38)
0.98 (0.74–1.3)
0.903
1 (0.76–1.4)
0.863
TT
55 (8.6)
12 (3.6)
0.3 (0.2–0.7)
0.004
0.3 (0.15–0.7)
0.003
CC + CT
322 (96.4)
580 (91.5)
0.4 (0.2–0.76)
0.005
0.3 (0.15–0.7)
0.003
Women
CC
197 (59)
259 (51)
Reference
Reference
CT
118 (36)
203 (40)
0.7 (0.6–1)
0.072
0.9 (0.6–1.2)
0.418
TT
17 (5)
47 (9)
0.5 (0.26–0.85)
0.013
0.5 (0.25–0.96)
0.04
CT + TT
135 (41)
250 (49)
0.70 (0.5–0.9)
0.016
0.7 (0.5–0.96)
0.028
CI, confidence interval; OR, odds ratio. Obesity in logistic regression was adjusted by age, gender (except in women model), glucose, triglycerides, LDL-C, and HDL-C levels.
