Association of Nuclear Factor-Erythroid 2-Related Factor 2, Thioredoxin Interacting Protein, and Heme Oxygenase-1 Gene Polymorphisms with Diabetes and Obesity in Mexican Patients

Table 6

Association of the rs2071749 polymorphism of the HMOX1 gene with obesity.

Variable	Obese, (%)	Nonobese, (%)		BMI
AA	261 (40)	410 (46)	0.026	28.9 ± 4.9	0.027
AG + GG	390 (60)	497 (54)		29.5 ± 5.3
Crude OR (95% CI)	1.25 (1.02–1.54)		0.026
OR adjusted (95% CI)	1.34 (1.06–1.7)		0.013
Beta coefficient/	0.063/0.03		0.023

BMI values are presented as mean ± SD. BMI, body mass index, CI: confidence interval, and OR: odds ratio.
Obesity in logistic regression was adjusted by age, gender, glucose, triglycerides, and LDL-C and HDL-C levels. Genotype was included as dominant model in logistic and multivariate analysis.
Linear regression of BMI as dependent variable was adjusted by age, gender, glucose, triglycerides, and LDL-C and HDL-C levels.