Association of Nuclear Factor-Erythroid 2-Related Factor 2, Thioredoxin Interacting Protein, and Heme Oxygenase-1 Gene Polymorphisms with Diabetes and Obesity in Mexican Patients

Table 7

Association of the rs6721961 polymorphism of the Nrf2 gene with diabetes in men.

Variable	Diabetic, (%)	Nondiabetic, (%)		Glucose
CC	203 (69)	271 (58)	0.011	126.6 ± 59	0.056
CA	79 (27)	171 (37)		116 ± 56
AA	12 (4)	23 (5)		105 ± 32
CA + AA	91 (31)	194 (42)	0.003	114.4 ± 53	0.031
Crude OR (95% CI)	0.62 (0.46–0.85)		0.003
OR adjusted (95% CI)	0.56 (0.38–0.82)		0.003
Crude beta coefficient	−0.078		0.031

Glucose values (mg⋅dL⁻¹) are presented as mean ± SD. CI: confidence interval; OR: odds ratio.
Diabetes in logistic regression was adjusted by age, triglycerides, and LDL-C and HDL-C levels. Genotype was included as dominant model in logistic and linear regression.
⁢ value when comparing each genotype.
⁢ value in comparison of CC with CA + AA.