Kaempferol Attenuates Myocardial Ischemic Injury via Inhibition of MAPK Signaling Pathway in Experimental Model of Myocardial Ischemia-Reperfusion Injury

Table 1

Effect of KMP on biochemical parameters.

Groups	MDA (nmole/g tissue)	GSH (µmole/g tissue)	SOD (U/mg protein)	CAT (U/mg protein)	LDH (U/L)	CK-MB (U/L)
Sham	63.27 ± 2.50	1.15 ± 0.08	5.48 ± 0.39	6.63 ± 0.38	450.62 ± 28.85	414.12 ± 19.84
IR-C	99.97 ± 3.49	0.62 ± 0.04	2.94 ± 0.51	3.87 ± 0.42	742.04 ± 20.00	616.64 ± 21.16
KMP 20 + IR	79.04 ± 3.8	0.94 ± 0.06	5.3 ± 0.5	5.91 ± 0.47	589.58 ± 20.02	513.18 ± 20.62
KMP 20 ps	67.96 ± 2.81	1.06 ± 0.06	5.33 ± 0.33	6.17 ± 0.3	499.19 ± 20.86	466.41 ± 18.42

MDA: malondialdehyde; GSH: reduced glutathione; SOD: superoxide dismutase; CAT: catalase; LDH: lactate dehydrogenase; CK-MB: Creatine Kinase-MB isoenzyme. IR-C: ischemia-reperfusion control; KMP 20 + IR: kaempferol 20 mg/kg/day + ischemia-reperfusion; KMP 20 ps: kaempferol 20 mg/kg/day per se. The values are expressed as mean ± SEM; in each group; , versus sham; ; versus IR-control.