Hepatocyte Growth Factor Reduces Free Cholesterol-Mediated Lipotoxicity in Primary Hepatocytes by Countering Oxidative Stress

Figure 2

Cholesterol overload in primary mouse hepatocytes affects HGF levels and c-Met expression. A high cholesterol diet induces a decrease in serum HGF levels (a), quantified by ELISA, and c-Met expression assayed by immunofluorescence, original magnification, 200X (b). c-Met immunofluorescence quantification (c). Images are representative of at least three independent experiments. Each column represents mean ± SEM of at least four independent experiments. versus Chow.

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