Hepatocyte Growth Factor Reduces Free Cholesterol-Mediated Lipotoxicity in Primary Hepatocytes by Countering Oxidative Stress

Figure 3

HGF decreases the oxidative stress induced by the cholesterol overload. (a) Quantification of 2′,7′-dichlorofluorescein fluorescence: data are reported as fluorescence arbitrary units (FAU). Each point represents mean ± SEM of at least four independent experiments. (b) Representative confocal images of peroxides content determined by 2′,7′-dichlorofluorescein fluorescence in Chow and HC cells treated or not with HGF for 24 h. versus Chow, versus nontreated HC cells.

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