AP39, a Mitochondria-Targeted Hydrogen Sulfide Donor, Supports Cellular Bioenergetics and Protects against Alzheimer’s Disease by Preserving Mitochondrial Function in APP/PS1 Mice and Neurons

Figure 7

AP39 generates H₂S in WT mice and AP39 increased H₂S levels in APP/PS1 mice. (a) The contribution of AP39 to H₂S production in the cortex and hippocampus of WT mice. (b) AP39 increased H₂S levels in APP/PS1 mice. , compared with the WT group; , compared with the control group (H₂O).

(a)

(b)