Effects of Hyperoxia on Oxygen-Related Inflammation with a Focus on Obesity

Figure 2

Effects of hypoxia on the secretion of key proteins in mice and human adipocytes and in adipose tissue of C57BL/6J mice (green up arrow) increased and (red down arrow) decreased protein in response to hypoxia). ADIPOQ: adiponectin; ANGPTL4: Angiopoietin-like protein 4; APLN: Apelin; DPP4: dipeptidyl peptidase-4; GLUT-1: Glucose Transporter 1; HIF-1α: hypoxia-inducible factor-1α; IL-6: Interleukin-6; IL-10: Interleukin-10; LEP: leptin; MIF: macrophage migration inhibitory factor; MCP-1: monocyte chemoattractant protein-1; PAI-1: plasminogen activator inhibitor-1; VEGF: vascular endothelial growth factor; TNF-α: tumor necrosis factor-α.