Toll-Like Receptor 4 Reduces Oxidative Injury via Glutathione Activity in Sheep

Figure 4

Contents of GSH and oxidative stress-related genes in TLR4 transgenic sheep monocytes/macrophages. (a) GSH content measurements, (b) GSSG content measurements, (c) GSH/GSSG ratio calculations, (d) RT-PCR detection of AP-1 and antioxidative-related gene expression. Data represent mean ± SE. ^{a,b,c,d;A,B,C,D}Different superscripts indicate significantly different values between groups (). Wt, wild type; Tg-1, Tg-2, and Tg-3 were transgenic sheep that had 1, 2, or 3 copies of TLR4.

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