Lipoxin A4 Preconditioning Attenuates Intestinal Ischemia Reperfusion Injury through Keap1/Nrf2 Pathway in a Lipoxin A4 Receptor Independent Manner

Figure 5

Lipoxin A4 attenuated intestinal epithelium cells apoptosis and finally increased rat survival rate. Representative photomicrographs showing fluorescent staining (a, 400x) of cytochrome C (green) or DAPI (blue) in intestinal epithelium cells and fluorescence intensity were measured (b). Cell apoptosis was also measured by using TUNEL assay (c, 400x) and TUNEL positive cells were counted (d). Each bar represents the mean ± SEM ( per group); the survival rate (e) was determined during 72 hours after reperfusion; per group. , , one-way ANOVA with Tukey test.

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