Metformin Decreases Reactive Oxygen Species, Enhances Osteogenic Properties of Adipose-Derived Multipotent Mesenchymal Stem Cells <i>In Vitro</i>, and Increases Bone Density <i>In Vivo</i>

<div>Results of MuASCs immunophenotyping. Obtained cells were positive for the mesenchymal markers CD29, CD44, CD73, and CD105 and show lack of expression for the hematopoietic marker CD45. Each marker was stained with a specific antibody and secondary antibodies conjugated with atto-488; nuclei were counterstained with DAPI. Magnification ×100, scale bar: 250 <i>μ</i>m.</div>

Oxidative Medicine and Cellular Longevity

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Figure 1

Figure 1: Metformin Decreases Reactive Oxygen Species, Enhances Osteogenic Properties of Adipose-Derived Multipotent Mesenchymal Stem Cells <i>In Vitro</i>, and Increases Bone Density <i>In Vivo</i> 

Figure 1 | Metformin Decreases Reactive Oxygen Species, Enhances Osteogenic Properties of Adipose-Derived Multipotent Mesenchymal Stem Cells In Vitro, and Increases Bone Density In Vivo 