Preclinical Antileukemia Activity of Tramesan: A Newly Identified Bioactive Fungal Metabolite

Figure 1

TR induces a dose-dependent reduction in cell count in hematopoietic cell lines. Jurkat and OCI-AML3 cells were exposed to increasing concentrations of TR for the indicated time points. Cell counts and viability were then assessed by trypan blue exclusion counting. Results are expressed as the average ± SD of seven independent experiments.