REGγ Contributes to Regulation of Hemoglobin and Hemoglobin δ Subunit

Figure 1

REGγ-mediated Hb degradation in multiple hemopoietic tissues. (a) Hb levels in bone marrow, (b) liver, and (c) spleen tissues from two different REGγ^+/+ and REGγ^−/− mice. Protein was extracted and analyzed using Western blot against anti-Hb and anti-REGγ antibodies. β-Actin was use as internal control. The quantification analysis was conducted and shown as a graph. Left: Western blot. represents the number of mice in each genotype. All the mice were sacrificed at age of 1-2 weeks old. Right: quantification analysis. Data are presented as means ± SEM from three independent experiments. versus control.

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