Antioxidants from Plants Protect against Skin Photoaging
Table 2
Antioxidants involved in protection from photoaging.
Antioxidants
Class
Bioactive compound
Skin protection from photoaging
Ref
Synthetic
Nitroxides (mimetics of SOD)
Tempol
Protection from UVA- and UVB-induced damage in vitro and in vivo Inhibition of extracellular matrix degradation and preservation of collagen production in vitro
Protection of HaCaT cells from UVB irradiation through attenuation of the caspase pathway Counteraction of UVB damages in hairless mice Reduction of skin wrinkling and skin oxidative stress
Protection of HaCaT cells from UVA irradiation through attenuation of inflammation and activation of apoptosis Antioxidant, photoprotection, antiaging, antipigmentary effects on the skin